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目的分析男性不育症患者细胞遗传学结果,探讨染色体异常对男性不育的影响。方法采用G显带方法,对468例男性不育症患者进行外周血染色体检查。结果468例不育症患者,101例染色体异常,染色体异常率为21.58%。染色体异常病例中,79.20%为Y染色体数目异常(80/101),6.93%为Y染色体结构异常(7/101);0.89%(11/101)为常染色体结构异常,2.97%(3/101)为性反转。结论染色体异常,尤其是Y染色体异常对男性生育能力有重要的影响。
Objective To analyze the cytogenetic results of male infertility and explore the effect of chromosomal abnormalities on male infertility. Methods Using G banding method, 468 cases of male infertility patients with peripheral chromosomal examination. Results 468 cases of infertility patients, 101 cases of chromosomal abnormalities, chromosomal abnormalities was 21.58%. Among the chromosomal abnormalities, 79.20% had abnormalities of Y chromosome (80/101), 6.93% were Y chromosome abnormalities (7/101), 0.89% (11/101) were autosomal abnormalities, 2.97% (3/101) ) For the sexual inversion. Conclusion Chromosomal abnormalities, especially Y chromosome abnormalities, have an important impact on male fertility.