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作者观察了新生儿早期接触母乳中的风疹病毒对嗣后风疹疫苗免疫接种的血清反应性和免疫学应答的影响.将150名产妇分为两组.第1组100人,于怀孕期间多次检测风疹抗体均为阴性,在其分娩后1~3天,皮下注射0.5ml风疹减毒活疫苗.第2组50人,风疹抗体阳性(天然免疫),产后不接种风疹疫苗,为对照组.80%的新生儿为母乳喂养,其余则为人工喂养.所有婴儿在15~18月龄时皮下接种单剂风疹减毒活疫苗.用ELISA检测产妇及其婴儿免疫前后的血清、乳汁及鼻咽分泌物
The authors looked at the effects of rubella virus in early neonatal exposure to breast milk on the serological and immunological response to subsequent rubella vaccine immunization.150 mothers were divided into two groups, group 1, 100, tested multiple times during pregnancy Rubella antibodies were negative, in its 1 to 3 days after delivery subcutaneously injected 0.5ml live attenuated rubella vaccine. Group 2 50, rubella antibody positive (natural immunity), postpartum non-vaccination rubella vaccine for the control group. % Of newborns were breastfed and the rest were artificially fed.All infants were immunized subcutaneously with a single dose of live attenuated rubella vaccine at 15-18 months of age.Serum, milk, and nasopharyngeal secretion were measured by ELISA before and after immunization Things