本文采用ＷＨＯ的标准方法发现１例葡萄糖－６－磷酸脱氢酶（Ｇ６ＰＤ）活性严重缺乏但不伴有非球形红细胞溶血的傣族男性患者，其酶活性相当于正常的２．１３％，电泳迁移率慢速，２－脱氧６－磷酸葡萄糖（２ｄＧ６Ｐ）、６－磷酸半乳糖（Ｇａｌ－６Ｐ）及脱氨基辅酶Ⅱ（ｄｅａｍｉｎｏ－ＮＡＤＰ）利用率均明显增高，辅酶Ⅱ米氏常数（ＫｍＮＡＤＰ）增高，葡萄糖６－磷酸米氏常数（ＫｍＧ６Ｐ）降低，ｐＨ曲线呈双峰，热稳定性明显降低，与国内外报道的Ｇ６ＰＤ变异型比较，认为是１种新型，命名为Ｇｄ（－）傣族临沧型〔Ｇｄ（－）Ｄａｉ－Ｌｉｎｃｈａｎｇ〕 In this paper, we use WHO standard methods to find a case of Dai male patients with severe G6PD activity deficiency but not associated with non-spherical erythrocytes hemolysis, the enzyme activity equivalent to the normal 2.13%, electrophoretic mobility The rates of 2dG6P, Gal-6P and deamino-NADP were significantly increased and KmNADP was increased (KmG6P) decreased, the pH curve showed a bimodal peak, and the thermostability was significantly decreased. Compared with the G6PD variant reported at home and abroad, it was considered as a new type named Gd (-) Dai Lincang Type [Gd (-) Dai-Linchang]