论文部分内容阅读
报告体外隔肌起搏（ＥＤＰ）治疗慢性阻塞性肺病（ＣＯＰＤ）。结果：１１慢性肺心病重度Ⅱ型呼衰者应用ＥＤＰ后ＰａＯ＿２无明显提高（Ｐ＞０．４），ＰａＣＯ＿２明显降低（Ｐ＜０．０５）。２６例肺心病轻度Ⅱ型呼衰者应用ＥＤＰ后ＰａＯ＿２明显升高（Ｐ＜０．００１），ＰａＣＯ＿２明显降低（Ｐ＜０．００１）。１５例肺心病Ⅱ型呼衰者应用ＥＤＰ加高频喷射通气（ＨＰＪＶ）后，ＰａＯ＿２明显升高，ＰａＣＯ＿２增高不显著（Ｐ＞０．０５）。３２例ＣＯＰＤ者应用ＥＤＰ治疗（３０ｍｉｎ／ｄ）３０天后，ＰａＯ＿２、ＰａＣＯ＿２、肺活量（ＶＣ），每分通气量（ＭＶ）和６分钟步行距离（６ＭＤ）明显改善。表明ＥＤＰ是ＣＯＰＤ的有效康复疗法，但对肺心病严重Ⅱ型呼衰患者无效。
Extracorporeal diaphragm pacing (EDP) is reported for the treatment of chronic obstructive pulmonary disease (COPD). Results: PaO2 significantly increased (P> 0.4) and PaCO 2 decreased significantly (P <0.05). PaO2 significantly increased (P <0.001) and PaCO 2 decreased significantly (P <0.001) in ED patients with pulmonary heart disease mild type Ⅱ respiratory failure. After treatment with EDJ plus high frequency jet ventilation (HPJV), the PaO_2 and PaCO_2 increased significantly in 15 patients with type Ⅱ respiratory failure of pulmonary heart disease (P> 0.05). PaO2, PaCO 2, vital capacity (VC), minute ventilation (MV) and 6-minute walking distance (6MD) were significantly improved in 32 COPD patients treated with EDP for 30 days. EDP is an effective rehabilitation of COPD, but not for patients with severe pulmonary heart disease type Ⅱ respiratory failure.