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例一:男,45岁,患预激综合征。入院前2周始服胺碘酮,第1周600mg/d,第2周减为400mg/d,服药第14天,出现弥漫淤点和淤斑,血小板(BPC)15×10~9/L,其他血液检查、肝肾功能和抗核抗体正常。停服胺碘酮,用胺碘酮淋巴细胞刺激试验(LST)刺激率高达400%,而用奎尼丁等则正常。给强的松治疗好转。例二:男,69岁,因淤斑住院。10年前行二尖瓣置换术。因多源性室早,于入院前12天始服胺碘酮,前7天600mg/d,后5天400mg/d,BPC 13×10~9/L,凝血酶原时间17秒,WBC和Hb正常,原淋巴细胞转化受胺碘酮强烈刺激。停用胺碘酮,给强的松40
Example 1: Male, 45 years old, suffering from pre-excitation syndrome. Amiodarone was given 2 weeks before admission, 600 mg / d in the first week and 400 mg / d in the second week. On the fourteenth day after administration, diffuse bruises and ecchymosis were found. Platelets (BPC) 15 × 10 ~ 9 / L , Other blood tests, liver and kidney function and anti-nuclear antibody normal. Amiodarone was stopped and stimulated with amiodarone lymphocyte stimulation test (LST) up to 400%, while quinidine was normal. Give strong pine treatment improved. Example 2: Male, 69 years old, hospitalized for ecchymosis. Ten years ago, mitral valve replacement surgery. Amiodarone was given 12 days before admission, 600 mg / d for the first 7 days, 400 mg / d for the next 5 days, 13 × 10 9 / L for BPC, 17 seconds for prothrombin time, Hb is normal, the original lymphocyte transformation strongly stimulated by amiodarone. Disable amiodarone, to prednisone 40