患者男,40岁,因右眶内囊肿于1983年1月29日,在强化加局麻下行右额部开颅右眶内囊肿切除术。术后为降低颅内压,以20%甘露醇250毫升(青岛制药厂生产,批号821014)静脉滴入,10分钟后滴入约170毫升,患者心悸、胸闷,全身出现荨麻疹、搔痒。考虑为术中输血反应,即给肌注非那根25毫克,静滴氟美松10毫克,20分钟后恢复正常。当日下午再次静滴甘露醇,5分钟后滴入约100毫升,患者面色苍白,大汗淋漓,呼吸急 Male, 40 years old, right orbital cyst on January 29, 1983, underwent augmentation plus local anesthesia right forehead craniotomy orbital cyst excision. After surgery to reduce intracranial pressure, with 20% mannitol 250 ml (Qingdao Pharmaceutical Factory production lot number 821014) intravenous infusion of about 170 ml after 10 minutes, the patient palpitations, chest tightness, systemic urticaria, itching. Consider intraoperative transfusion reactions, intramuscular injection that non-root 25 mg, intravenous flumethazine 10 mg, returned to normal after 20 minutes. Mannitol intravenously again in the afternoon, drip about 5 minutes after the 100 ml, pale, sweating, breathlessness