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目的通过分析微波诱导高温灭活治疗脊柱转移肿瘤患者的手术时间、出血量、功能状态及病情转归情况，评价微波高温诱导原位灭活技术治疗后患者的预后，并为治疗方案的选择提供理论依据、数据支持。方法分析自2008~2013年间入住我院的脊柱转移肿瘤临床病例，记录每例患者的各项临床资料，于治疗前及治疗后2w、1个月、3个月、6个月、1年分别进行相应指标的监测。所有病例按治疗手段不同分为微波诱导高温原位灭活治疗(实验组)、常规手术治疗(对照组)2个治疗组。并根据Tokuhashi外科修正评分得分归为5~8、9~11、12~15分3个分数段，分别进行比较两治疗组患者术前术后各项指标。结果①9~11分、12~15分术中出血量实验组少于对照组有统计学差异(<0.05)。12~15分病例中实验组手术时间少于对照组具备统计学差异(<0.05)。②Karnofsky功能状态评分结果显示两治疗组Tokuhashi修正评分5~8分病例术后1个月，9~11分术后0.5个月、6个月，12~15分段术后0.5个月时得分实验组高于对照组并具有统计学意义。③Frankle脊髓损伤分级比较结果显示术后6个月时两治疗组间患者神经功能状态差异具有统计学意义。结论微波诱导高温原位灭活技术治疗脊柱转移瘤可以明显减少肿瘤切除过程中的出血，缩短手术时间。并且具有手术创伤小、术后恢复快、瘤灶灭活较彻底等优点。在手术治疗脊柱转移瘤方面具有明显的优势及良好的应用前景。“,”Objective To evaluate of microwave induced hyperthermia in situ inactivation treatment of patient's prognosis,and find the theory basis and data support for the options of treatment,by analyzing the microwave-induced hyperthermia inactivation treatment of spinal metastases patients with the volume of blood loss,functional status and disease outcome.Methods We have analyzed of metastatic spinal tumor clinical cases in our hospital since 2008 to 2013.Monitored the clinical data before surgery and the 0.5th month,1st month, 3rd months,6th months,12th month after surgery of each patient.Al cases are divided into two treatment groups:microwave induced hyperthermia inactivation treatment(experimental group),the conventional surgical treatment(control group),and acoording to Tokuhashi reviced surgical score,divided the cases into three scores paragraph.Then compared the informations of two treatment groups with preoperative and postoperative indicators.Results ①In Tokuhashi revised surgical score,paragraph 9~11,12~15,blood loss in the surgery of experimental group was less than the control group,( <0.05).In paragraph 12~15,operation time of the experimental group was less than the control group( <0.05);②Karnofsky performance status(Kps)results showed that, the score of the experimental group was higher than control group and had statistical significance in Tokuhashi revised score paragraph 9~11 at postoperative 0.5th months, 6th months. In paragraph 5~8 and 12~15 the Kps score of the experimental group was also higher at the 0.5th months after surgery; ③Frankle spinal cord injury scale comparison showed that, the patients' neurological status had statistical significance at the 6th months postoperation between the two treatment groups. Conclusion Microwave induced hyperthermia in situ inactivation treatment of spinal metastases may significantly reduce blood loss in the process of tumor resection, shorten the operation time.And it has the advantages of minimal y invasive, rapid postoperative recovery, metastases inactivated thoroughly. From al above,This technique has very obvious advantages and good prospects in the surgical treatment of spinal metastases.