作者应用Dexter长期培养体系结合短期培养,观察其对急性非淋巴细胞增殖的影响。发现白血病细胞集落生成单位(CFU-L)在本体系中迅速减少,于4～6周完全消失,而正常对照组的粒单核细胞集落生成单位(CFU-GM)可存活8周以上。在急性粒细胞白血病(AML)细胞培养中2～4周出现CFU-GM。加重组人巨噬细胞集落刺激因子(rh-CSF-1)后CFU-L的回收值较不加组低(P<0.01),消失时间也早。非贴壁及 The author uses Dexter long-term culture system combined with short-term culture to observe its impact on acute non-lymphocyte proliferation. Found that leukemia cell colony forming units (CFU-L) in the system rapidly decreased in 4 to 6 weeks completely disappeared, while the normal control group of mononuclear cell colony forming units (CFU-GM) can survive more than 8 weeks. CFU-GM appears 2 to 4 weeks in acute myeloid leukemia (AML) cell culture. The recovery of CFU-L was less (P <0.01) and the disappearance time was earlier in the group of rh-CSF-1. Non-adherent and