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46例急性心肌梗塞患者行尿激酶(UK)、链激酶(SK)静脉溶栓治疗。根据其在梗塞前一周内有无心绞痛发作分为A、B两组。对两组的临床、随访观察资料及心肌酶学CK测定的峰值进行分析,表明A组室速室颤、心力衰竭、心原性休克、院内死亡率均低于B组(p<0.05),并且CK峰值亦较后者明显减低(p<0.01)。提示:梗塞前心绞痛对溶栓治疗的急性心肌梗塞患者的左心室功能有保护作用,有利于溶栓治疗后再灌注的建立,并减少梗塞面积。
Forty-six patients with acute myocardial infarction received urokinase (UK) and streptokinase (SK) intravenous thrombolysis. According to its in the week before the infarction with angina pectoris is divided into A, B two groups. The clinical and follow-up data of the two groups and the peaks of myocardial enzymological CK were analyzed. The results showed that ventricular fibrillation, heart failure, cardiogenic shock and in-hospital mortality were lower in group A than in group B (p <0.05) And CK peak was also significantly lower than the latter (p <0.01). Tip: Pre-infarction angina protects left ventricular function in patients with thrombolytic therapy of acute myocardial infarction, facilitates establishment of reperfusion after thrombolytic therapy, and reduces infarct size.