论文部分内容阅读
目的:研究肿瘤特异性生长因子(TSGF)在肺癌诊断中的价值及肺癌患者放疗前后血清TSGF含量变化。方法:47例肺癌患者与100例正常体检人群血清TSGF含量检测;34例肺癌患者进行放疗,放疗1个疗程前后采血测定TSGF含量。结果:肺癌组患者血清TSGF含量及阳性率显著高于健康对照组(P<0.01);放疗的肺癌患者中,有效者血清TSGF含量较放疗前显著降低(P<0.01),TSGF水平下降幅度与肿瘤缩小程度之间无正相关关系(P>0.05);无效者血清TSGF含量则显著升高(P<0.01)。结论:血清TSGF是一种敏感性较高的肿瘤标志物,对肺癌患者诊断、治疗效果评价有重要的临床意义。
Objective: To investigate the value of tumor specific growth factor (TSGF) in the diagnosis of lung cancer and the change of serum TSGF level in patients with lung cancer before and after radiotherapy. Methods: Serum levels of TSGF were detected in 47 lung cancer patients and 100 healthy subjects. Blood samples were obtained from 34 lung cancer patients before and after radiotherapy and radiotherapy. Results: Serum TSGF levels and positive rates in patients with lung cancer were significantly higher than those in healthy controls (P <0.01). The levels of serum TSGF in patients with lung cancer were significantly lower than those before radiotherapy (P <0.01) There was no significant correlation between the degree of tumor shrinkage (P> 0.05) and the level of TSGF in inactive patients (P <0.01). Conclusion: Serum TSGF is a highly sensitive tumor marker, which has important clinical significance for the diagnosis and treatment of lung cancer patients.