恶性胸腹水染色体及脱落细胞学检查的临床价值

来源 :医学理论与实践 | 被引量 : 0次 | 上传用户:akk871204
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为比较恶性胸腹水染色体及脱落细胞学检查的临床价值。对住院的48例恶性胸腹水患者进行胸腹水细胞悬液短期培养制备染色体,观察其数目,同时将离心后胸腹水涂片、染色、镜下观察其组织类型。结果前者阳性42/48(87.5%),其中多倍体及超二倍体占89.6%(>10%),后者阳性30/48(62.5%),两种方法结合阳性率44/48(91.7%)。结果表明前者阳性率高于后者(P<0.01),两种方法结合比单用一种检查方法确诊率明显提高,并对两项检查意义进行讨论。 To compare the clinical value of chromosomes and exfoliated cytology in malignant pleural effusions. Forty-eight hospitalized patients with malignant pleural effusion and ascites were subjected to short-term culture of the thoracic/ascitic fluid cell suspension to prepare chromosomes and their numbers were observed. At the same time, the thoracic/ascitic fluid smear, staining, and microscopic observation of the tissue types were performed after centrifugation. The former was 42/48 (87.5%) positive, and the polyploid and hyperdiploid were 89.6% (>10%), and the latter was 30/48 (62.5%). The positive rate of the two methods combined was 44/48 ( 91.7%). The results showed that the positive rate of the former was higher than the latter (P<0.01). The combination of the two methods significantly improved the diagnosis rate compared with the single examination method, and discussed the significance of the two tests.
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