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目的探讨尼莫地平对高血压脑出血的治疗效果的影响。方法选择高血压脑出血患者44例,分为治疗组和对照组,2组基线资料具有可比性。2组均给予常规治疗。治疗组在常规治疗基础上给予尼莫地平静脉滴注,10d后改为口服,共用30d,比较2组患者的血肿量及中国卒中评分(CSS)。结果治疗15、30d后血肿体积治疗组〔(7.03±2.98)、(5.73±1.24)cm3〕较对照组〔(9.36±3.98)、(7.38±3.07)cm3〕显著缩小(P均<0.05),治疗30d后治疗组CSS〔(7.41±3.56)分〕明显低于对照组〔(11.03±3.80)分〕(P<0.05)。结论尼莫地平治疗高血压脑出血疗效良好。
Objective To investigate the effect of nimodipine on the treatment of hypertensive intracerebral hemorrhage. Methods 44 patients with hypertensive intracerebral hemorrhage were selected and divided into treatment group and control group. The baseline data of two groups were comparable. Both groups were given routine treatment. The treatment group was given nimodipine intravenously on the basis of routine treatment, and was orally administered after 10 days, sharing for 30 days. The hematoma volume and stroke score (CSS) of two groups were compared. Results Compared with the control group [(9.36 ± 3.98), (7.38 ± 3.07) cm3〕, the volume of hematoma volume treatment group (7.03 ± 2.98, 5.73 ± 1.24 cm3) was significantly reduced after 15 and 30 days of treatment (all P <0.05) After treatment for 30 days, the CSS (7.41 ± 3.56) points in the treatment group were significantly lower than those in the control group (11.03 ± 3.80 points) (P <0.05). Conclusion Nimodipine is effective in treating hypertensive intracerebral hemorrhage.