论文部分内容阅读
本文介绍反相高效液相色谱法测定血中奎尼丁浓度及其临床应用。以咖啡因为内标物。线性回归方程为 Y=0.9871X-0.1547,r=0.9974。奎尼丁绝对回收率不低于88%。在奎尼丁血浓度为0.645mg/ml 时,天内测定值的变异系数是4.1%。测定低限约为50ng/ml 血浆。
This article describes the reversed-phase high performance liquid chromatography to determine the concentration of quinidine in blood and its clinical application. With caffeine as internal standard. The linear regression equation is Y = 0.9871X-0.1547, r = 0.9974. Quinidine absolute recovery of not less than 88%. When the quinidine blood concentration was 0.645 mg / ml, the coefficient of variation for the intra-day assay was 4.1%. Lower limit of determination of about 50ng / ml of plasma.