胰岛素瘤在一般人群中发生率约为1/10万;多为良性腺瘤,少数为增生或癌。主要临床表现为低血糖所致精神、神经症状,以“一过性症状”为特征。由于症状非特异性,且变化多端,易被延误诊断,致引起不可逆的精神、神经损害。如能早期诊治,则大多预后良好。本文对本院自1962年以来共收治手术证实的胰岛素瘤42例作了临床分析,并对诊断和治疗等加以总结和探讨。 The incidence of insulinoma in the general population is about 1/10 million; mostly benign adenomas, a small number of hyperplasia or cancer. The main clinical manifestations of hypoglycemia caused by mental, neurological symptoms, characterized by “transient symptoms.” As the symptoms of non-specific, and varied, easily delayed diagnosis, causing irreversible mental and neurological damage. If early diagnosis and treatment, most of the prognosis is good. In this paper, 42 cases of insulinomas confirmed by operation since 1962 in our hospital were analyzed, and the diagnosis and treatment were summarized and discussed.