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某些继发性神经病的发病与血浆免疫球蛋白的异常有着密切的关系.近年来已在单株系丙球病伴神经病变患者的血浆中发现与神经组织有异常亲合性的免疫球蛋白,在某些癌性神经病患者血浆中发现抗神经元核抗体和抗小脑蒲氏细胞抗体,在Lyme病患者血浆中检出了能与神经组织抗原免疫结合的抗螺旋体Borrelia burgdorferi抗体.
The incidence of some secondary neuropathy is closely related to the abnormality of plasma immunoglobulin.In recent years, immunoglobulin with abnormal affinity with nerve tissue has been found in the plasma of patients with single strain of Crohn’s disease and neuropathy , Anti-neuron nuclear antibodies and anti-cerebellar anti-cerebellar antibodies were found in the plasma of some cancerous neuropathies, and Borrelia burgdorferi antibodies against Helicobacter burgdorferi were detected in the plasma of patients with Lyme disease.