论文部分内容阅读
目的 分析全身性炎症反应综合征 ( SIRS)向多脏器功能不全综合征 ( MODS)的发展过程 ,探索 MODS的防治策略。 方法 回顾性分析 2 80例老年急腹症患者的 SIRS和 MODS的临床资料。 结果 老年急腹症患者入院时 ,SIRS的发生率 4 1 .4 % ,其后 MODS发生率 1 2 .9% ,病死率1 0 .3 % ;经治疗 (包括手术和保守治疗 ) 4 8小时后 ,仍伴有 SIRS的患者 3 9例中 ,1 5例发展为 MODS。2 80例老年急腹症患者中 ,发生 MODS共 1 7例 ( 6.1 % ) ,死亡 1 4例 ( 82 .3 % )。 结论 早期诊断SIRS,特别注意分析治疗 4 8h后仍伴有 SIRS的患者的原因 ,积极调控机体炎症反应 ,是改善老年急腹症患者预后的关键。
Objective To analyze the development of systemic inflammatory response syndrome (SIRS) to multiple organ dysfunction syndrome (MODS) and to explore the strategy of prevention and treatment of MODS. Methods The clinical data of SIRS and MODS in 280 elderly patients with acute abdomen were retrospectively analyzed. Results The incidence of SIRS in elder patients with acute abdomen was 41.4%, followed by MODS incidence of 12.9% and fatality rate of 10.3%. After treatment (including surgery and conservative treatment) 48 hours Of the 39 patients still with SIRS, 15 developed MODS. Of the 80 elderly patients with acute abdomen, 17 (6.1%) had MODS and 14 (82.3%) died. Conclusion The early diagnosis of SIRS, with special attention to analysis of the reasons for the patients with SIRS after 48 h treatment, and the active regulation of the inflammatory reaction are the keys to improve the prognosis of elderly patients with acute abdomen.