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乳腺癌是女性最常见的肿瘤相关性死亡原因之一,全世界每年约有135万妇女发生乳腺癌,约33万妇女死于乳腺癌[1]。研究发现HER2基因在25%~30%乳腺癌患者中扩增,其过度活化与乳腺癌的发生发展有着重要关联[2]。针对乳腺癌HER2的分子靶向治疗是近年来出现的继化疗和内分泌治疗后的又
Breast cancer is one of the most common causes of cancer-related death in women. About 1.35 million women worldwide develop breast cancer each year, and about 330,000 women die of breast cancer. [1] The study found that HER2 gene amplification in 25% to 30% of breast cancer patients, the overexpression of breast cancer is closely related to the occurrence and development [2]. Molecular targeted therapy for breast cancer HER2 appears in recent years after chemotherapy and endocrine therapy