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目的探讨梗阻性黄疸对肝脏血流动力学的影响.方法采用彩色多普勒血流显象仪对20例梗阻性黄疸患者的肝固有动脉和门静脉血流进行定量测量,并与20例正常人进行对比分析.结果梗阻性黄疸患者肝固有动脉的峰值流速(cm/s,92±15vs69±19,P<005)、血流量(mL/min,714±363vs305±121,P<001)显著高于正常人;门静脉血管内径(cm,125±024vs104±019,P<001)及门脉充血指数(cm×s,0141±0013vs0119±0013,P<001)明显高于正常人.但门静脉血流量及峰值流速则低于正常人.结论彩色多普勒血流显象仪探讨梗阻性黄疸时肝脏血流动力学改变的较理想非创伤性方法,根据其有效循环血容量的改变可初步判断梗阻性黄疸的预后
Objective To investigate the effect of obstructive jaundice on hepatic hemodynamics. Methods Quantitative measurement of hepatic artery and portal vein blood flow in 20 patients with obstructive jaundice by color Doppler flow imaging was performed and compared with 20 normal subjects. Results The peak flow velocity of hepatic artery (cm / s, 92 ± 15 vs 69 ± 19, P <005) and blood flow (mL / min, 714 ± 363 vs 305 ± 121, P <001) were significantly higher in patients with obstructive jaundice In normal subjects, portal vein diameter (cm, 125 ± 024vs104 ± 019, P <001) and portal venous congestion index (cm × s, 0141 ± 0013vs0119 ± 0 013, P <0 01) was significantly higher than normal. However, portal flow and peak flow were lower than normal. Conclusion The color Doppler flow imaging instrument is an ideal and noninvasive method to investigate the hemodynamic changes of liver during obstructive jaundice. According to the change of effective circulating blood volume, the prognosis of obstructive jaundice