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吗啡具有明显的呼吸抑制作用,但其机制尚不清楚。自七十年代发现脑内阿片受体和内源性阿片肽以来,对吗啡呼吸抑制机制的探讨又受到重视。本文介绍这一研究的概况和目前的进展。
Morphine has obvious respiratory depression, but its mechanism is not yet clear. Since the discovery of intracerebral opioid receptors and endogenous opioid peptides in the seventies, more attention has been paid to the mechanism of respiratory depression of morphine. This article presents an overview of the research and current progress.