罗伯逊易位(RT)是两条同源或非同源染色体间的整臂易位。在人类,于两条近端着丝粒染色体以外发生这种易位的很少见。RT可以是单着丝粒或双着丝粒的,但在多数情况下不能可靠地确定。在双着丝粒RT,第二个着丝粒常是失活的。虽RT是最常见的人染色体异常,新生儿中约有1/1 000,但其来源很少引起注意。本文讨论了RT的不同起源,特别是不同近端着丝粒染色体参与RT的非随机性。我们对8个人的966个Q带中期相作了近 Robertson’s translocation (RT) is the arm-arm translocation between two homologous or non-homologous chromosomes. In humans, this translocation occurs rarely outside the two proximal centromere chromosomes. RT can be either monocentric or dicentric, but in most cases can not be reliably determined. In dicentric RT, the second centromere is often inactivated. Although RT is the most common human chromosomal abnormality, about 1 in 1000 newborns, but its source rarely pay attention. This article discusses the different origins of RT, in particular, the different near-centromeric chromosomes involved in the non-randomness of RT. We are close to 966 Q-band metaphase of 8 people