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为掌握和了解黄果茄植物提取物对鱼类和大鼠的急性毒性 ,本研究进行了常规的鱼类急性毒性试验和大鼠急性经口毒性试验。结果表明 ,黄果茄植物提取物对鱼类稀有鱼句鲫的急性毒性试验 ,在 0 .2 70 mg/ L浓度中 ,2 4h稀有鱼句鲫死亡率为 0 % ;在 17.2 8mg/ L中 ,2 4h稀有鱼句鲫死亡率为 10 0 % ;SX对稀有鱼句鲫 2 4h L C5 0 为 2 .0 2 mg/ L ,95 %的可信限为 1.33~ 3.0 6 mg/ L。对大鼠急性经口毒性的绝对致死剂量为 2 15 0 mg/ kg· bw,L D5 0 为 794mg/ kg· bw,95 %可信限为 5 84~10 80 mg/ kg· bw,属低毒类。
In order to understand and understand the acute toxicity of Huangguo plant extracts to fish and rats, this study conducted routine acute toxicity tests of fish and acute oral toxicity in rats. The results showed that the acute toxicity test showed that the mortality of Carassius auratus gibelio was0% at0.270mg / L for 24 hours and 17.28mg / L , And the mortality rate of crucian carp in 24 hours was 10%. The SX was 2.24 mg L -1 and the 95% confidence limit was 1.33-3.06 mg / L for 24 h LX0. The absolute lethal dose for acute oral toxicity in rats was 2 15 0 mg / kg · bw, the L D5 0 was 794 mg / kg · bw, the 95% confidence limit was 5 84 to 10 80 mg / kg · bw, Poisonous.