药物引起的肾损害日趋增多，主要表现为肾毒性反应及过敏反应［1］。到目前为止，至少有140多种药物可致肾损害，大约25％的肾功能衰竭为药源性LI。本文分析1995～1997年我院173例药源性肾损害情况，以期提高临床工作者对药物肾毒性的认识。临床资料一、病例选择取1995～1997年 Drug-induced renal damage is increasing, mainly as nephrotoxic response and allergic reactions [1]. So far, at least 140 drugs can cause kidney damage, and about 25% of renal failure is drug-induced LI. This article analyzes 173 cases of drug-induced renal damage in our hospital from 1995 to 1997, with a view to raising awareness of clinical nephrotoxicity. Clinical data A case selection from 1995 to 1997