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葡萄状菌病是一种少见的、慢性、化脓性疾病,临床及组织病理常易误诊为真菌感染.病原菌为细菌,常见的是金黄色葡萄球菌,也可培养出绿脓假单胞菌、大肠杆菌、变形杆菌、芽胞杆菌等.典型的组织病理改变是由病原菌组成的成簇“颗粒”.本病常发生在四肢,亦见于躯干、面部和肛周,可累及内脏,尤其是肺,此外亦可发生在口腔粘膜,舌、脑、肠和眶部.本文报道4例皮肤葡萄状菌病,临床表现呈慢性化脓性肉芽肿样过程,组织学检查可见“颗粒”.
Staphylococcus aureus is a rare, chronic, suppurative disease, clinical and histopathological often misdiagnosed as fungal infections.Patients are bacteria, common is Staphylococcus aureus, but also can be cultured Pseudomonas aeruginosa, Escherichia coli, Proteus, Bacillus, etc. The typical histopathological changes are clusters of “pathogenic bacteria.” The disease often occurs in the extremities, also found in the trunk, face and perianal crevices, and can involve the viscera, especially Lung, in addition can also occur in the oral mucosa, tongue, brain, intestine and orbital.In this paper, four cases of skin Staphylococcus aureus were reported, the clinical manifestations of chronic pyogenic granuloma-like process, histological examination shows “particles.”