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瘦素是肥胖基因的编码产物,通过与其受体结合在体内发挥多种生物学作用,具有调节摄食、能量代谢、生殖、造血、免疫等生理功能,参与炎性反应、损伤修复等病理生理过程。近年来的研究发现,瘦素与人体多种疾病密切相关,深入研究瘦素的生物学活性及对人体多种疾病的作用机制,可为防治人体某些难治性疾病提供新的策略或途径。
Leptin is a coding product of obesity gene. It plays a variety of biological roles in the body by binding with its receptor, and has the physiological functions of regulating food intake, energy metabolism, reproduction, hematopoietic and immune, and is involved in pathophysiological processes such as inflammatory reaction and injury repair . In recent years, the study found that leptin and the human body is closely related to a variety of diseases, in-depth study of leptin biological activity and mechanism of action on a variety of human diseases, for the prevention and treatment of some refractory diseases in the human body to provide new strategies or ways .