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目的 :为探讨银杏叶片对慢性肺心病患者肺动脉高压的影响。方法 :将 42例缓解期肺心病患者分为两组 ,治疗组 2 7例 ,口服银杏叶片 ,每日 3次 ,每次 2片 (80mg) ,对照组 15例 ,口服安慰剂 ,每日 3次 ,每次 2片 ,两组病例分别于治疗前、治疗第 2 0天和第 40天时分别作心脏彩超 1次 ,测三尖瓣区血液返流速度 (Vt)计算出收缩期肺动脉压 (SPAP)。结果 :统计学分析显示治疗组治疗后Vt有非常显著下降 (P <0 .0 1) ,Vt2 、SPAP有显著下降 (P <0 .0 5 ) ;对照组治疗前后各指标无明显变化 ,两组比较 ,银杏叶片与安慰剂治疗效果有显著差异。结论 :本研究表明银杏叶片可显著降低SPAP ,可用于肺心病的防治。
Objective: To investigate the effect of ginkgo leaf on pulmonary hypertension in patients with chronic cor pulmonale. Methods: 42 cases of remission of pulmonary heart disease were divided into two groups, the treatment group 27 cases, oral ginkgo leaf 3 times a day, two tablets (80mg), the control group of 15 patients, oral placebo, daily 3 Times, each 2, two groups of patients were treated before treatment, treatment 20 days and 40 days, respectively, for the time of echocardiography 1, measured tricuspid regurgitation velocity (Vt) calculated systolic pulmonary artery pressure SPAP). Results: Statistical analysis showed that Vt in treatment group decreased significantly (P <0.01), Vt2 and SPAP decreased significantly (P <0.05), while there was no significant change in control group before and after treatment Group, ginkgo leaves and placebo treatment effect was significantly different. Conclusion: This study shows that Ginkgo biloba can significantly reduce the SPAP, can be used for the prevention and treatment of pulmonary heart disease.