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前列腺癌(prostate cancer,PCa)是欧美国家男性发病率第一和死亡率第二的恶性肿瘤[1]。由于PCa自然病程较长,临床症状隐匿,许多患者被发现时已处于晚期,因此,PCa的早期诊断成为临床上关注的焦点。血清前列腺特异性抗原(prostate-spec ific antigen,PSA)对PCa的敏感性和特异性较
Prostate cancer (PCa) is the number one malignant tumor in men and women in Europe and the United States [2]. Due to the long natural history of PCa, the clinical symptoms of occult, many patients were found in advanced stage, therefore, early diagnosis of PCa has become the focus of clinical attention. Sensitivity and specificity of serum prostate-specific antigen (PSA) to PCa