中国人脐膨出流行病学分析

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目的:为了解中国人脐膨出(omphaloceles)的流行特征和基本状况,为进一步研究该畸形提供参考资料。方法:中国出生缺陷监测中心在1987年1992年以医院为单位对孕28周至产后7天的围产儿进行监测,对监测到的522例脐膨出病例进行流行病学分析。结果:中国人脐膨出平均发生率为116/万,其中浙江省和新疆维吾尔自治区的发生率最高,分别为216/万和204/万,宁夏回族自治区最低,为012/万。脐膨出的发生无城乡和性别差异。单发脐膨出占52%,多发占48%,脐膨出围产儿死亡达52%,多发病例达72%。与脐膨出伴发的畸形以无肛、脊柱裂和无脑儿等多见。脐膨出的产前确诊率为17%。结论:中国人脐膨出的发生率水平与国外报道的基本一致,但产前确诊率低,脐膨出常以多发形式出现,且死亡率高,在诊断和治疗该畸形时应警惕其他畸形的存在。 Objective: To understand the epidemiological features and basic conditions of omphaloceles in Chinese, provide references for further study of this deformity. Methods: China Birth Defect Monitoring Center monitored the perinatal children in the hospital from 28 weeks pregnant to 7 days postpartum in 1992 in 1992, and conducted epidemiological analysis on 522 cases of umbilical swelling observed. Results: The average incidence of umbilical swelling was 116 / 10 000 in China, of which the highest incidence was found in Zhejiang Province and Xinjiang Uygur Autonomous Region, with 216% and 204% respectively, while the lowest in Ningxia Hui Autonomous Region was 0  12 / million. Umbilical swelling occurs without urban-rural and gender differences. Single umbilical swelling accounted for 52%, 48% were multiple, umbilical swelling perinatal death rate of 52%, 72% of cases of multiple attacks. With umbilical bulge associated with deformity without anus, spina bifida and anencephaly and more common. Prenatal diagnosis of umbilical swelling rate was 17%. Conclusion: The incidence of umbilical swelling in Chinese is basically consistent with that reported in foreign countries. However, the prenatal diagnosis rate is low, umbilical swelling often occurs in multiple forms, and the mortality rate is high. Other deformities should be observed in the diagnosis and treatment of this deformity The presence.
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