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目的 观察植物素9501 杀钉螺的效果和毒性。方法 实验室杀成螺、幼螺、螺卵试验采用浸杀法;现场草洲采用喷洒法;垸内沟渠用沿边铲草浸杀法;毒性试验用胃灌法和皮肤、粘膜刺激法。结果 9501 5m g/ L和10m g/ L实验室浸杀成螺、幼螺、螺卵的死亡率均达 1000% ;现场浸杀成螺死亡率分别为 980% 和 1000% ;10m g/ L垸内沟渠铲草浸杀活螺平均密度下降率为946% ;喷洒40g/m 2 死亡率为600% ;小白鼠口服急性毒性 L D50大于5 000m g/kg;对家兔眼结膜有轻微刺激,对皮肤刺激不明显;5m g/ L使鱼全部死亡,4m g/ L对鱼安全。结论 9501 浸杀钉螺、幼螺、螺卵效果好,喷洒杀螺作用差;对人、畜毒性低,对鱼有一定毒性;与油茶皂素比较,具有剂型稳定,不回潮结块,易保管等优点。
Objective To observe the effect and toxicity of Phytocins 9501 to kill snails. Methods Lab kill spire, snail, spiro egg test using immersion method; field CaoZhou sparging method; embankment ditch with shovel grass dip method; toxicity test with gastric irrigation and skin, mucosal stimulation method. Results The mortalities of snail and baby snail were all 1000% at 9501 5m g / L and 10m g / L, respectively. The mortality rate of snail oncomelania were 980% and 1000 %; 10m g / L embankment trenches shoveling dip snail average density reduction rate was 94 6%; spray 40g / m 2 mortality was 60 0%; mice acute oral toxicity L D50 greater than 5 000m g / kg; there is a slight irritation to the conjunctiva in rabbits and no obvious irritation to the skin; 5m g / L causes all the fish to die and 4m g / L is safe for the fish. Conclusion 9501 dip snail, snail, spiro egg effect is good, spraying spiro effect is poor; to humans, animal toxicity is low, a certain toxicity to the fish; compared with Camellia saponin, with a stable dosage form, no resurgence lumps, easy to custody Etc.