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[目的]分析伴有中央-颞区棘波的儿童良性癫痫(BECT)的临床和脑电图特点。[方法]回顾性分析40例BECT患儿的临床资料,包括临床表现和脑电图变化。[结果]发病年龄2～12岁,平均(7.87±4.52)岁,好发于4～10岁,7～9岁为高峰年龄。38例(95.0%)为非频繁性发作,2例(5.0%)为短期内频繁发作。31例(77.5%)患儿在睡眠中发作,9例(22.5%)患儿在清醒与睡眠时均有发作。部分性运动发作30例(75.0%),7例(17.5%)发作时表现为直一阵挛。脑电图表现以尖波、尖-慢波、棘波,以尖-慢波为主。痫样放电位于中央和/或颞区34例(85.0%),位于单侧13例(22.5%),痫样放电位于左、右侧半球相互转移27例(67.5%)。睡眠时较清醒时放电多,以非快速眼动睡眠(NREM)Ⅰ、Ⅱ期最为明显。[结论]BECT临床发作与睡眠密切相关,BECT发作时其临床和EEG具有特征性改变,行睡眠脑电诊断BECT有助于BECT的治疗和预后判断。
[Objective] To analyze the clinical and electroencephalographic features of benign epilepsy (BECT) in children with central-temporal spikes. [Methods] The clinical data of 40 patients with BECT were retrospectively analyzed, including clinical manifestations and EEG changes. [Results] The onset age ranged from 2 to 12 years, with an average of (7.87 ± 4.52) years old, which mainly occurred in 4 to 10 years old and peaked at 7 to 9 years old. Thirty-eight patients (95.0%) had seizures and two patients (5.0%) were seizures in the short term. Thirty-one (77.5%) children had seizures during sleep, and nine (22.5%) children had seizures during both awake and sleep. Some cases of seizures in 30 cases (75.0%), 7 cases (17.5%) seizures showed a straight clonus. EEG showed spikes, sharp - slow waves, spikes, sharp - slow-wave-based. Epileptiform discharges were found in 34 (85.0%) of the central and / or temporal regions, 13 (22.5%) in unilateral and 27 (67.5%) in the left and right hemispheres. More than when the sleep discharge more awake, non-REM sleep I (NREM) the most obvious. [Conclusion] The clinical seizure of BECT is closely related to sleep. The clinical and EEG features of BECT during the onset of BECT are characteristic changes. Diagnosing BECT with sleep EEG is helpful for the treatment and prognosis of BECT.