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目的:分析TORCH的检验结果,探讨TORCH感染对于自然流产患者的影响。方法:选取2010年1月到2013年12月来南京市第一医院检查的无自然流产史孕妇300例(对照组),并选择同期有自然流产史孕妇300例(观察组),使用ELISA检验法检测所有孕妇TORCH抗体,对比分析两组阳性率。结果:观察组血清中的风疹病毒(RV)、单纯疱疹病毒(HSV-Ⅱ)、巨细胞病毒(CMV)、弓形虫(TOX)的阳性率分别为12.00%、52.00%、27.67%、3.33%,明显高于对照组的2.00%、3.00%、2.67%、1.00%,差异有统计学意义(P<0.05);观察组流产、死胎和早产的比率分别为37.67%、7%、11.67%,明显高于对照组的7.67%、0.33%、0.67%,差异有统计学意义(P<0.05);观察组HSV-Ⅱ和CMV所致不良妊娠发生率分别为58.30%﹑59.04%,与RV、TOX所致不良妊娠发生率66.67%、50.00%比较,差异有统计学意义(P<0.05)。结论:TORCH病原体或者病毒抗体阳性率的孕前检测对于预防自然流产有重要的临床意义。
Objective: To analyze the TORCH test results and explore the impact of TORCH infection on spontaneous abortion patients. Methods: A total of 300 pregnant women without spontaneous abortion were selected from the First Hospital of Nanjing City from January 2010 to December 2013, and 300 pregnant women with spontaneous abortion during the same period (observation group) TORCH antibody test for all pregnant women, comparative analysis of two groups of positive rate. Results: The positive rates of RV, HSV-Ⅱ, CMV and TOX in the observation group were 12.00%, 52.00%, 27.67%, 3.33% , Which was significantly higher than that of the control group (2.00%, 3.00%, 2.67% and 1.00% respectively) (P <0.05). The rates of miscarriage, stillbirth and premature delivery in the observation group were 37.67%, 7% and 11.67% (P <0.05). The incidences of adverse pregnancy in HSV-Ⅱ and CMV groups were 58.30% and 59.04% respectively, which were significantly lower than those in RV, The incidence of adverse pregnancy caused by TOX was 66.67%, 50.00%, the difference was statistically significant (P <0.05). Conclusion: The prenatal detection of the positive rate of TORCH pathogen or virus antibody is of important clinical significance in preventing spontaneous abortion.