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对青岛市１４１０名健康儿童随意早餐后２ｈ尿钙／肌酐（Ｃａ／Ｃｒ）比值和２４ｈ尿钙定量进行测定。提出以随意早餐后２ｈ尿Ｃａ／Ｃｒ比值≥０．２２，２４ｈ尿钙定量＞０．１ｍｍｏｌ／ｋｇ，作为本地区儿童高钙尿症诊断的标准；据此在本组被调查儿童中检出特发性高钙尿症（ＩＨ）３９例，发病率为２．７７％，无性别差异；钙负荷试验示ＩＨ以肠吸收型为主。同时发现肠吸收型ＩＨ病儿红细胞膜钙泵活性增高，而肾脏漏出型降低，与对照组比较Ｐ＜０．０１或０．０５，推测体内（尤其是小肠和肾小管上皮细胞）钙泵活性异常在ＩＨ发病机制中起重要作用。
The levels of urinary calcium / creatinine (Ca / Cr) and urinary calcium and urinary calcium were measured at 2 hours after random breakfast in 1410 healthy children in Qingdao. Proposed random breakfast 2h urinary Ca / Cr ratio ≥ 0.22, 24h urinary calcium> 0.1mmol / kg, as the diagnostic criteria for children with hypercalciuria in the region; accordingly detected in this group of children surveyed Idiopathic hypercalciuria (IH) in 39 cases, the incidence was 2.77%, no gender differences; calcium load test showed IH to intestinal absorption type based. Also found that intestinal absorption of IH children with erythrocyte membrane calcium pump activity increased, while the leakage of the kidneys decreased compared with the control group P <0.01 or 0.05, speculated that the body (especially the small intestine and tubular epithelial cells) calcium pump activity Abnormalities play an important role in the pathogenesis of IH.