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目的:探讨化疗对恶性肿瘤患者血糖的影响。方法:取江苏省溧水县人民医院2008年1月~2011年3月收治的153例恶性肿瘤患者,采取回顾性分析方法对合并2型糖尿病的患者比例,以及化疗前、化疗中、化疗后血糖变化情况进行临床观察。结果:153例患者中,化疗前诊断糖尿病者占9.15%(14/153),未诊断糖尿病者139例,13.67%(19/139)化疗后空腹血糖升高,其中糖耐量异常者11人,占7.91%(11/39),诊病者5人,占3.60%(5/139),一过性血糖升高3人,占2.16%(3/153)。结论:恶性肿瘤患者接受化疗可以引起血糖升高,甚至出现糖耐量异常或2型糖尿病,需进一步分析原因,探索该现象与恶性肿瘤患者治疗效果和预后的关系。
Objective: To investigate the effect of chemotherapy on blood glucose in patients with malignant tumor. Methods: A total of 153 patients with malignant tumors who were treated in Lishui People’s Hospital of Jiangsu Province from January 2008 to March 2011 were retrospectively analyzed. The proportion of patients with type 2 diabetes mellitus and the blood glucose before and after chemotherapy, Changes in clinical observation. Results: Of the 153 patients, there were 9.15% (14/153) patients diagnosed with diabetes before treatment, 139 patients without diabetes mellitus, and 13.67% (19/139) patients with fasting plasma glucose after chemotherapy. Among them, 11 patients had impaired glucose tolerance, Accounting for 7.91% (11/39), 5 were diagnosed, accounting for 3.60% (5/139), 3 were transient hyperglycemia, accounting for 2.16% (3/153). CONCLUSIONS: Chemotherapy in patients with malignant tumors can cause hyperglycemia and even impaired glucose tolerance or type 2 diabetes mellitus. Further analysis of the causes is needed to explore the relationship between this phenomenon and the therapeutic effect and prognosis of patients with malignant tumors.