The global navigation satellite system(GNSS) has become an important space infrastructure. Following GPS and GLONASS, Europe and China have been building their own global navigation satellite system, respectively, GALILEO and Compass. In order to consolidate the leadership of GPS in the globe, United States is gradually upgrading the traditional GPS. Simultaneously, Russia is also intensively restoring full performance of GLONASS. With the advancement of international satellite navigation system, satellite navigation frequency resources are already in short supply, and the design and use of the navigation signals are more sophisticated and complex due to commercial, disaster relief and other reasons. Since there may be many navigation signals in the same basic bandwidth, the coexistence of multiple systems and the combined application make intersystem mutual interference become the focus research. Under this background, the satellite navigation system mutual interference evaluation system needs to be established urgently to meet and support the compatibility and interoperability of the GNSS system. In the paper, through the performance analysis of the GNSS signal acquisition, carrier tracking, data demodulation and code tracking, the equivalent carrier to noise ratio model based on spectrum isolation coefficient is established, and the theoretical system of the GNSS signal mutual interference is proposed according to the mechanism, and the mutual interference of GPS, GALILEO and Compass system is analyzed and assessed. Following the GPS and GLONASS, Europe and China have been building their own global navigation satellite system, respectively, GALILEO and Compass. In order to consolidate the leadership of GPS in the globe , United States is gradually upgrading the traditional GPS. Simultaneously, Russia is also intensively restoring full performance of GLONASS. With the advancement of international satellite navigation system, satellite navigation frequency resources are already in short supply, and the design and use of the navigation signals are more sophisticated and complex due to commercial, disaster relief and other reasons. Since there may be many navigation signals in the same basic bandwidth, the coexistence of multiple systems and the combined application make intersystem mutual interference become the focus research. Under this background, the satellite navigation system mutual interference evaluation sys tem needs to be established urgently to meet and support the compatibility and interoperability of the GNSS system. In the paper, through the performance analysis of the GNSS signal acquisition, carrier tracking, data demodulation and code tracking, the equivalent carrier to noise ratio model based on spectrum isolation coefficient is established, and the theoretical system of the GNSS signal mutual interference is proposed according to the mechanism, and the mutual interference of GPS, GALILEO and Compass system is analyzed and assessed.