Studies in Vitro on Cytotoxic Action of Asbestos on Rat Alveolar Macrophages

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The cytotoxicities of Xingkang chrysotileasbestos, Canada chrysotile asbestos (UICC),silicon and carbon dust on rat alveolar ma-crophages (MP) during 5, 10, 16 h incubationwere investigated. The phagocytosis and func-tion of MP were observed by microscope andSEM. The results showed the decrease of cellsurvival rate with culture time in each group.But the silical group showed a faster thanthe others. The Canadian group was next.There existed a significant difference betweenthe dust and the control groups. A significant change was noted in the The cytotoxicities of Xingkang chrysotileasbestos, Canada chrysotile asbestos (UICC), silicon and carbon dust on rat alveolar ma-crophages (MP) during 5, 10, 16 h incubation were investigated. The phagocytosis and func tion of MP were observed by microscope and SEM. The results showed the decrease of cellsurvival rate with culture time in each group.But the silical group showed a faster thanthe others. The Canadian group was next.There existed a significant difference betweenthe dust and the control groups. A significant change was noted in the
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