论文部分内容阅读
目的 进一步探讨母婴之间巨细胞病毒 (CMV)的感染与传播。方法 对 36对母婴配对的尿和 16例母乳标本进行CMV分离 ,其中 2 6例检测CMVIgM抗体。 结果 婴儿尿CMV分离阳性率为 47 2 % ,其中 1个月内、～ 4个月、～ 1岁婴儿阳性率分别为 0、6 0 0 %和 33 3 % ,存在显著差异 (χ2 =6 5 7,P <0 0 5 )。母亲母乳CMV分离阳性率为 75 % ,显著高于其尿的排毒率 5 6 % (χ2 =2 3 74,P <0 0 1)。在喂养方式中 ,纯母乳喂养儿CMV阳性率为 5 7 7%与非纯母乳喂养儿的 2 0 %相比 ,差异显著 (χ2 =4 12 ,P <0 0 5 )。在不同病种中 ,婴儿肝炎综合征(婴肝 )患儿CMV培养及IgM的阳性率为 5 5 % ,支气管肺炎患儿CMV阳性率则高达 80 % ,而 6例其它病种患儿仅 2例阳性。结论 母乳是婴儿获得CMV感染的主要来源。婴肝及小婴儿肺炎以CMV感染为主
Objective To further explore the infection and transmission of cytomegalovirus (CMV) between mother and baby. Methods Thirty-six pairs of maternal and infant urine and 16 breast milk samples were isolated by CMV. Twenty-six of them were tested for CMVIgM antibody. Results The positive rate of CMV isolation in infants was 47.2%. The positive rates of CMV in infants were 0,6 0 0% and 33 3% respectively at 1 month, 4 months and 1 year old (χ2 = 65 7, P <0 0 5). The positive rate of CMV in mother’s breast milk was 75%, which was significantly higher than that of urine (56%, 2374, P <0.01). Among feeding methods, the positive rate of CMV in exclusive breastfeeding children was 57.7%, which was significantly different from 20% in non-exclusively breastfeeding children (χ2 = 4 12, P 0 05). In different diseases, the positive rate of CMV and IgM in infantile hepatitis syndrome (infant liver) was 55%, and the positive rate of CMV in children with bronchopneumonia was as high as 80%, while only 6 of 6 cases of other diseases Positive cases. Conclusion Breast milk is the main source of CMV infection in infants. Infant liver and infant pneumonia are mainly CMV infection