论文部分内容阅读
具体地说:有以灶性病变为主的肺纤维化,病理上多见灶性病变,而同时也有间质病变,但比较轻微;还有以间质为主的肺纤维化,间质变化较重,但也有灶性病变,其灶的直径较小,间质纤维化可明显见重。灶性为主的纤维化,在肺中占位容积相对较少,病人症状和呼吸功能丧失不甚明显(如矽肺);间质性为主的肺纤维化,其病变占肺容积较大,患者症状出现早,肺功能丧失较重(如混合性尘肺)。因粉尘的理化性状不同,所引起的组织反应也不同,纤维化程度不一,纤维化形态也不能相同。就病灶来说,有圆形透明性变的,也有非典型的不整形的病灶;有胶原纤维排列不整,也有网织纤维;还有以网织纤维为主,并有少量胶原纤维。
Specifically: There are focal lesions of pulmonary fibrosis, pathological focal lesions more common, but also interstitial lesions, but relatively minor; there are interstitial lung fibrosis, interstitial changes Heavier, but also focal lesions, the lesser diameter of the lesion, interstitial fibrosis can be seen seriously. Focal fibrosis in the lungs occupy a relatively small volume, the patient’s symptoms and respiratory function loss is not obvious (such as silicosis); interstitial lung fibrosis, the lesion accounted for a larger lung volume, Patients with symptoms of early, severe loss of lung function (such as mixed pneumoconiosis). Due to different physical and chemical properties of dust, the tissue reaction caused by different, varying degrees of fibrosis, fibrosis morphology can not be the same. On the lesion, there is a circular transparency change, there are atypical non-plastic lesions; collagen fibers arranged in an irregular, but also reticular fibers; there are mainly reticular fibers, and a small amount of collagen fibers.