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甲型肝炎疫苗及免疫球蛋白均对甲型肝炎病毒 (HAV)感染具有防御作用 ,但 HAV疫苗可提供完全保护作用。有效的接种方法与抗 HAV抗体形成的关系尚不清楚。作者用针头注射法与喷射注射法接种 HAV疫苗以确定血清阳转率或抗 HAV抗体水平的差异。 作者将 32 0名成年志愿者随机分为
Hepatitis A vaccines and immunoglobulins both have a protective effect against hepatitis A virus (HAV) infection, but HAV vaccines provide complete protection. The relationship between effective vaccination methods and anti-HAV antibody formation is unclear. The authors vaccinated HAV vaccines by needle injection and jet injection to determine differences in seroconversion rates or anti-HAV antibody levels. The authors randomly assigned 320 adult volunteers