原发性血小板减少性紫癜(idiopathicthrombocytopenic purpura,ITP)是免疫性血小板减少症的一种。它有别于其他免疫性血小板减少症,后者的原因已明。而 ITP的原因尚未阐明,但已公认其病因是通过免疫机制所致。现就 ITP 的免疫学研究、诊断和治疗的进展介绍如下。ITP 的免疫学研究1951年 Harrington 等首先证明约60%的ITP 病人血清中存在抗血小板抗体,目前对 ITP的免疫学机制已有较深入的了解,并知道体液 Idiopathic thrombocytopenic purpura (ITP) is a kind of immune thrombocytopenia. It is different from other immune thrombocytopenia, the latter has been the reason. The reason for ITP has not yet been elucidated, but the cause is known to be caused by the immune mechanism. The progress of ITP immunology research, diagnosis and treatment is presented below. ITP Immunology Research Harrington et al first demonstrated in 1951 that anti-platelet antibodies were present in the sera of about 60% of ITP patients and that the current immunological mechanisms of ITP have been well understood and that body fluids