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一、原发性免疫缺乏疾病中的 IgE 合成异常(1)Wiskott-Aldrich 综合征:此综合征的特点为易感染,巨核细胞性血小板减少性紫癜和对多糖抗原的体液反应受损。另外,这类患者尚有搔痒性湿疹样皮疹。与之相一致的是血清 IgE 浓度常升高和对吸入
First, IgE synthesis in primary immunodeficiency disorders (1) Wiskott-Aldrich syndrome: This syndrome is characterized by susceptible infections, megakaryocytic thrombocytopenic purpura and humoral responses to polysaccharide antigen damage. In addition, these patients have a pruritic eczematous rash. Consistent with this is the often elevated serum IgE concentration and inhalation