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多发性肌炎和皮肌炎(PM-DM)是骨胳肌的炎症性疾患。作者复习了500例PM-DM,均未提及有原发肺疾患。从1956年起共报告31例伴有间质性肺炎的PM-DM,本文报告6例,并作了资料复习。PM-DM诊断标准为:(1)特征性的近端肌肉无力、疼痛。(2)骨胳肌酶升高,(3)肌肉活检有PM-DM的证据,(4)无肌病家族史。原发肺疾患是通过胸片、肺活检或尸检来确定。本文病例女4男2,年龄32～64岁,平均49.5岁。有4例开始症状为呼吸困难,有或无咳嗽,比肌肉或皮肤症状早3～24月;有2例呼吸困难分别出现于确诊PM后之20及5月。X线观察:全部胸片均有弥漫线条状间质浸润,肺底最明显。此外,3
Polymyositis and dermatomyositis (PM-DM) are inflammatory disorders of the skeletal muscle. The authors reviewed 500 cases of PM-DM, none of which mention primary lung disease. Since 1956, a total of 31 cases of PM-DM with interstitial pneumonia were reported. Six cases were reported in this paper and the data were reviewed. PM-DM diagnostic criteria are: (1) characteristic proximal muscle weakness, pain. (2) increased skeletal muscle enzymes, (3) evidence of muscle biopsy with PM-DM, and (4) absence of a family history of myopathy. Primary lung disease is determined by chest radiography, lung biopsy or autopsy. This case 4 female 2 men, aged 32 to 64 years, mean 49.5 years old. Four patients had initial symptoms of dyspnea with or without coughing, 3 to 24 months earlier than muscle or skin symptoms, and 2 with dyspnea appearing in 20 and 5 months after diagnosis, respectively. X-ray observation: All chest radiographs were striated interstitial infiltration, the most obvious lung bottom. In addition, 3