,Neonatal lethality and recycling defect of transferrin receptor in mice with Syntaxin12/13 disrupti

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Dear Editor,Iron deficiency,documented by World Health Organization (WHO),is the most common nutritional deficiency,and accounts for ~50% of anemia globally.Iron-deficiency anemia is notably and frequently associated with chronic heart failure,chronic kidney disease,cancer and inflammatory bowel disease.According to WHO Global Health Estimates 2014 Summary,iron-deficiency anemia is a major and prevalent public health problem worldwide,which contributes to 0.2% mortality,especially mateal and child mortality.
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