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目的 :研究青年人急性心肌梗死 (AMI)的临床及冠脉病变特点 ,探讨导致青年人AMI的可能因素。方法 :对比分析AMI的危险因素、诱发因素、左室射血分数、冠状动脉造影 (CAG)结果。结果 :45岁以下者 2 9例 (A组 )与 6 0岁以上者 31例 (B组 )吸烟指数 >10 0者分别为 72 .4% ,41.9% ,饮酒指数 >15 0者分别为44 .8% ,16 .1% ,有冠心病阳性家族史者分别为 41.3% ,12 .9% ,有高血压史分别为 2 0 .7% ,5 1.6 % (均P <0 .0 5 ) ,有明确诱因者分别为 79.3 % ,33 .3 % (P <0 .0 1)。冠状动脉造影冠脉正常、1支病变、双支病变、3支病变A组分别为 2 4.1% ,44 .8% ,10 .3 % ,6 .9% ,B组分别为 3 .2 % ,16 .9% ,35 .5 % ,45 .2 % ,冠脉内有血栓者A、B组分别为 2 7.6 % ,6 .5 % ,左室射血分数 (EF) <5 0 %者分别为 13 .8% ,48.3 %。结论 :45岁以下AMI与吸烟、大量饮酒密切相关 ,其次为阳性家族史 ,其发病多有明确诱因。冠状动脉正常和单支病变较多 ,病变程度较轻。冠脉痉挛和血栓形成可能为其重要原因
Objective: To study the clinical features and coronary lesions in young patients with acute myocardial infarction (AMI) and explore the possible causes of AMI in young people. Methods: The risk factors, predisposing factors, left ventricular ejection fraction, and coronary angiography (CAG) results of AMI were compared and analyzed. Results: 29 (group A) and 31 (group B) patients aged 45 years and younger with smoking index> 10 were 72.4% and 41.9%, respectively, and alcohol index> 150 were 44 .8% and 16.1% respectively. The patients with positive family history of coronary heart disease were 41.3% and 12.9% respectively, and the history of hypertension were 20.7% and 5.16% respectively (all P <0.05) , With a clear inducement were 79.3%, 33.3% (P <0. Coronary artery angiography normal, 1 lesions, double-vessel lesions, 3 lesions in group A were 4.1%, 44.8%, 10.3%, 6.9%, respectively, B group were 3.2% 16.9%, 35.5% and 45.2% respectively. Patients with coronary artery thrombosis in group A and B were 7.66% and 6.5% respectively, and those with left ventricular ejection fraction (EF) <50% 13.8%, 48.3%. Conclusion: AMI under 45 years of age is closely related to smoking and heavy drinking, followed by a positive family history, and the incidence of more than a clear incentive. Coronary normal and single disease more lesions lesser degree. Coronary spasm and thrombosis may be its important reason