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泌尿道创伤、缺损或狭窄的修复与重建是目前临床上比较棘手的问题。因此,研究者一直试图寻找一种理想的修复泌尿道缺损的材料。小肠黏膜下层(smallintestinalsubmucosa,SIS)是一种新型的具有良好生物相容性和促组织再生特性的细胞外基质框架,在一系列动物实验研究中显示了良好的临床应用前景。随着对SIS研究的进一步深入,SIS在泌尿系统组织工程中的应用将更为广泛。
Urinary tract trauma, defect or stenosis repair and reconstruction is currently a more clinically difficult problem. Therefore, researchers have been trying to find an ideal material for repairing urinary tract defects. Small intestine submucosa (SIS) is a novel extracellular matrix with good biocompatibility and tissue regeneration. It has shown good clinical application in a series of animal experiments. With the further study of SIS, the application of SIS in urological tissue engineering will be more extensive.