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口服氨甲喋呤(MTX)在急性淋巴细胞性白血病(ALL)治疗的维持期中起较大的作用。一次口服剂量以后血清MTX水平变化很大,复发率和服后1小时低血清水平之间有关。因此,鉴定影响血清水平的因素是有用的。而血清浓度受排泄率和吸收率影
Oral methotrexate (MTX) plays a major role in the maintenance of acute lymphoblastic leukemia (ALL) therapy. After an oral dose of serum MTX levels vary greatly, the relapse rate and 1 hour after taking the low serum levels. Therefore, identifying factors that affect serum levels is useful. The serum concentration by the rate of excretion and absorption shadow