目的:建立网脱Ⅰ号口服液的制备工艺及其质量控制方法。方法:采用薄层色谱法鉴别口服液中的白芍、黄芪;用高效液相色谱法测定芍药苷、黄芪甲苷的含量,建立相对密度、pH等质控方法。结果:薄层色谱图中各斑点清晰,分离度好,易于识别;芍药苷平均回收率RSD为1.16%,黄芪甲苷平均回收率为1.46%。结论:该法简便、快速、灵敏度高、重复性好,可用于该制剂的质量控制。 OBJECTIVE: To establish the preparation process and quality control method of Wangde I oral liquid. Methods: Paeoniae radix and Astragalus mongholicus in oral solution were identified by TLC. The contents of paeoniflorin and astragaloside were determined by HPLC, and the relative density, pH and other quality control methods were established. Results: The spots in the TLC were clear and the resolution was good. The average recovery of paeoniflorin was 1.16% and the average recovery of astragaloside was 1.46%. Conclusion: The method is simple, rapid, sensitive, reproducible, and can be used for the quality control of the preparation.