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本文试用氮咪青霉素(mecillinam)及氟哌酸(norfloxacin)治疗15例经治不愈的耐药性伤寒患者。其中13例为二药联合治疗,另二例分别为氮(艹卓)咪青霉素及氟哌酸单独治疗。13例联合治疗者平均4.8天退热,3天肠出血停止,3.1天中毒性肠麻痹消失。4天中毒状态消失。停药后大便培养均三次阴性,治疗后血嗜酸性粒细胞计数均从零上升到正常。疗效满意。15例中3例复发。联合疗法疗程达2～3周者无一例复发。本文为伤寒耐药菌种感染者的治疗提供了切实有效的方法。
In this paper, 15 cases of drug-resistant typhoid fever were treated with mecillinam and norfloxacin. Among them, 13 cases were combined with two drugs, and the other two cases were treated with nitrogen (艹 Zhuo) mifepristone and norfloxacin alone. In the 13 co-treatment patients, the average fever was 4.8 days. The intestinal bleeding stopped after 3 days and the toxic intestinal paralysis disappeared in 3.1 days. 4 days the state of poisoning disappeared. After stopping the stool culture were negative three times, after treatment, blood eosinophil count rose from zero to normal. Satisfactory results. Three of 15 patients relapsed. Combination therapy course of up to 2 to 3 weeks without a recurrence. This article provides a practical and effective method for the treatment of typhoid-resistant bacteria.