苯胺或芳醚、N-卤代丁二酰亚胺(1.3倍摩尔量)、D-樟脑磺酸(0.5倍摩尔量)和1,3-双(1-金刚烷基)咪唑四氟硼酸盐(5%)在二噁烷中,室温反应24 h,制得相应的对位卤代产物。20例收率60%~98%。该方法适用于富电子芳烃对位的氯代、溴代或碘代反应,位阻较大的底物收率也较高。 Aniline or aryl ether, N-halogenosuccinimide (1.3-fold molar amount), D-camphorsulfonic acid (0.5-fold molar amount) and 1,3-bis (1-adamantyl) imidazole tetrafluoroborate Salt (5%) in dioxane at room temperature for 24 h to give the corresponding para-halogenated product. 20 cases of 60% to 98% yield. The method is applicable to the reaction of chloro, bromo or iodo on the para-position of the electron-rich aromatic hydrocarbon, and the yield of the substrate with larger steric hindrance is also higher.