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目的:观察左卡尼汀对慢性心功能不全患者心功能的影响。方法:选择慢性心力衰竭患者52例,将其分为治疗组(27例)和对照组(25例)。对照组采用常规治疗,治疗组常规治疗的同时使用左卡尼汀,15日为一个疗程,观察其左室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)、左室射血分数(LVEF)改善情况。结果:治疗组的总有效率为92.5%,对照组的总有效率为64.0%,两组有显著差异(P<0.05)。结论:左卡尼汀治疗慢性心功能不全疗效显著,无明显不良反应。
Objective: To observe the effects of levocarnitine on cardiac function in patients with chronic heart failure. Methods: 52 patients with chronic heart failure were selected and divided into treatment group (27 cases) and control group (25 cases). The patients in the control group were treated with conventional therapy. The patients in the treatment group were treated with levocarnitine routinely on the 15th, and the courses of LVEDD, LVESD, LVEF) to improve the situation. Results: The total effective rate was 92.5% in the treatment group and 64.0% in the control group, with significant difference between the two groups (P <0.05). Conclusion: L-carnitine treatment of chronic cardiac insufficiency significant effect, no significant adverse reactions.