论文部分内容阅读
目的:为改善宫颈癌综合治疗后患者生活质量,对宫颈癌综合治疗后HRT(激素替代治疗)效果。方法:将我院2012年4月至2014年7月行宫颈癌综合治疗后出现更年期症状患者90例作为研究对象,对照组28例;观察组62例,其中,雌孕激素联合治疗组25例,雌激素治疗组37例。在用药前、后更年期症状血脂、评分变化进行观察、比较。结果:相比于对照组,雌孕激素联合治疗组与雌激素治疗组在代谢、神经营养、精神情感相关的更年期症状显著降低,P<0.05;而雌孕激素联合治疗组与雌激素治疗组的更年期症状变化差异无明显差异,P>0.05;与用药前相比,血脂中高密度脂蛋白显著上升,P<0.05,低密度脂蛋白显著降低,P<0.05。结论:综合治疗后,宫颈癌患者行激素替代治疗能提高患者生活质量,减轻更年期症状。
Objective: To improve the quality of life of patients with cervical cancer after comprehensive treatment of cervical cancer combined treatment of HRT (hormone replacement therapy) effect. Methods: From April 2012 to July 2014 in our hospital, 90 cases of menopausal symptoms after cervical cancer treatment were included in the study. The control group was 28 cases and the observation group was 62 cases. Among them, 25 cases were treated with estrogen and progesterone combined treatment group , 37 cases of estrogen treatment group. In the medication before and after menopause symptoms of blood lipids, score changes were observed and compared. Results: Compared with the control group, estrogen and progesterone combined treatment group and estrogen treatment group in metabolism, neurotrophic, psycho-emotional menopausal symptoms significantly reduced, P <0.05; and estrogen and progesterone combination therapy group and estrogen treatment group The difference of menopausal symptoms had no significant difference, P> 0.05; Compared with pre-treatment, high-density lipoprotein in blood lipids increased significantly, P <0.05, low density lipoprotein decreased significantly, P <0.05. Conclusion: After combined treatment, hormone replacement therapy can improve the life quality of patients and reduce the symptoms of menopause.