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目的:了解我县初高中学生HBsAg感染状况和抗-HBs阳性状况,为今后学校乙肝防治提供科学依据。方法:对调查区域内5812名初一和高一入学新生静脉采血3 ml,分离血清,用ELISA法检测HBsAg、抗-HBs。结果:其中HBsAg阳性率为3.11%,抗-HBs阳性率为65.66%,初高中学生HBsAg阳性率高一高于初一,二者有差异性(χ2=23.95,P<0.05);而抗-HBs阳性率初一高于高一,二者差异有显著性(χ2=28.96,P<0.05);性别之间HBsAg阳性率(χ2=2.56,P>0.05)和抗-HBs阳性率(χ2=0.16,P>0.05)差异均无统计学意义。结论:学校应加强乙肝病毒预防知识的宣传力度,加强乙肝疫苗接种和入学入托查验接种证及查漏补种工作,提高乙肝疫苗基础免疫,是降低中学生HB-sAg阳性感染率,提高抗-HBs阳性率,以防止新的HBV感染者产生的主要措施。
OBJECTIVE: To understand HBsAg status and anti-HBs positive status of primary and secondary high school students in our county and to provide a scientific basis for future prevention and treatment of hepatitis B in school. Methods: 3 ml venous blood was collected from 5812 freshmen and high school freshmen in the survey area, serum was separated and detected by ELISA for HBsAg and anti-HBs. Results: The positive rate of HBsAg was 3.11% and the positive rate of anti-HBs was 65.66%. The positive rate of HBsAg in primary and secondary high school students was higher than that in primary school students (χ2 = 23.95, P <0.05) The positive rate of HBs in the first day was higher than that in the first one, the difference was significant (χ2 = 28.96, P <0.05). The positive rate of HBsAg (χ2 = 2.56, P> 0.05) 0.16, P> 0.05) showed no significant difference. Conclusion: The school should strengthen the publicity of hepatitis B virus prevention knowledge, strengthen the hepatitis B vaccination and enrollment check inoculation certificate and leak detection and replantation work to improve the basic immunity of hepatitis B vaccine, which is to reduce HB-sAg positive infection rate of middle school students and improve anti-HBs The positive rate, to prevent the new main cause of HBV infection.